Teva?s Copaxone Successor Fails in Latest Clinical Trial
By Naomi Kresge
Aug. 1 (Bloomberg) -- Teva Pharmaceutical Industries Ltd.?s experimental multiple sclerosis pill failed to reduce relapses more than placebo in a clinical trial, dealing a blow to the company?s effort to find a successor to an older drug.The medicine, laquinimod, missed the key goal of the study, the Petach Tikva, Israel-based drugmaker said today in a statement. By contrast, a third group of patients who got Avonex, an older injected treatment from Biogen Idec Inc., had fewer relapses than those who got a placebo. Teva?s American depositary receipts fell the most in more than three months.The study reported today, known as Bravo, is the second this year to show disappointing results for the medicine. Analysts expressed skepticism on a conference call with company executives that Teva would be able to win approval from the U.S. Food and Drug Administration for laquinimod. Teva said it aims to submit the drug by early next year.?Laquinimod is dead, if not regulatorily, then commercially,? READ MORE
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Prepare to get rid of acne in a few days. Although acne is a weak enemy, however there are many myths that makes getting rid of it, a distracted uncomfortable process. Reading this article will convince you that combating acne should not take more than 3-4 days, when understanding well how is it formed
Get rid of "Food Causes Acne" Myth:
As long as the underlying cause of any disease is not well established, any one can claim that certain foods are involved in its cause or exacerbation.
Thus we can find commonly unfavored food categories like, saturated fat, trans fat or high calorie intake, are accused of causing acne, based on observation of sporadic cases and conventional wisdom, and not credible scientific research to prove these claims.
Get rid of any thoughts about food (including chocolate and candy) when dealing with acne.
Get rid of "Acne and Diet" Myth:
Based on a theoretical sense, many diets that can affect hormones like insulin and androgens, or affect inflammation have not yielded sensible results, and more research is still needed to conclude a reliable scientific facts.
Getting Rid of Metabolic Aberrations associated with Acne:
Acne is mediated through some metabolic aberrations (produced by metabolic stress and not genetics), and you should understand them first.
During the teens and early 20's, fat plays a central role in metabolism. During this stage, the body extract energy mainly from fat under the influence of growth hormone.
Fat is also the starting material of synthesis of steroid hormones. Fat is largely supplied to the skin which increases in size greatly in this period of age.
Large quantities of fat are synthesized by the body to meet the needs of energy supply, formation of sex hormones and increased number and activity of sebaceous glands.
Coenzyme A plays a central role in fat (and carbohydrate ) metabolism. It is a part of the starting molecule of fat synthesis in the body, and a part of the starting molecule of the mitochondrial production of energy from both fat and carbohydrate.
The condition of metabolism that is predisposing your body to acne formation, allows existence of surplus fat including sebum in the ducts of the sebaceous glands, which dries up and clogs the skin pores producing acne.
Acne is a greasy situation, and if we increase fat breakdown we can reduce acne.
Get Rid of Acne by using Precursors of Coenzyme A
By now, you get the whole picture of acne formation, and you should have understood that increasing the amounts of available Coenzyme A, leads you to get rid of acne whenever it is formed.
To increase the availability of Coenzyme A, you should increase intake of its precursors orally or locally. I know it, I have been there, and I recommended this for years with great success.
Go read this article to know that Getting rid of acne is no more easier than that. You can get the whole practical picture of treatment to Get Rid of Acne
The body is like a highly functional machine. A machine as we well know must go through a period of complete readjustment, cleaning, realigning, refurbishing…
I know I need to lose weight, and I know how to lose weight, but I just can't motivate myself to do it. I come up with excuses. "I can't train at...
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On our Lab Notes page CalorieLab’s editors select and rank the day’s essential health news items in real time. Readers can suggest, vote and comment on items. Below are brief summaries of yesterday’s (July 31, 2011) Lab Notes items. To see today’s items, visit Lab Notes.
Elizabeth Karmel, creator of the group Girls at the Grill, is discouraging the gender stereotype of women cooking and men grilling.
A new study discovers how yoga reduces the pain and stress that accompanies fibromyalgia.
A new first of its kind study correlates increased muscle mass with a decreased risk of pre-diabetes. This is good news for at-risk patients who find it difficult to lose weight but who want to improve fitness levels.
(By CalorieLab editors)
Are you over weight and considering weight-loss surgery? Have you had weight loss surgery and are now left with excess skin? Maverick Television...
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