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Whats the connection between obesity and diabetes

A paper in the Journal of Cell Metabolism (March 2005), shows how being overweight can cause diabetes. Being overweight fills your fat cells so they can?t store much more fat. Then the body stores fat in muscles and liver. This causes muscles to produce a chemical called PPAR-Alpha which causes muscles cells to bring in and burn more fat, which prevents muscles from using sugar for energy. So blood sugar levels rise. The fat in muscle cells also blocks insulin receptors from grabbing onto insulin which prevents insulin from driving sugar into cells. This drives blood sugar levels even higher.



Daniel P. Kelly, director of the Center for Cardiovascular Research at the Washington University in St Louis, genetically engineered two different types of mice: one type that made extra PPAR-alpha in their muscles and another that lacked that molecule. They found that mice that overproduce PPAR-alpha become diabetic even though they are thin, because the muscle cells can burn only fat for energy, which prevents muscle cells from using sugar. This causes blood sugar levels to rise very high and the mice to become diabetic. On the other hand, mice who did not make PPAR-alpha grew very fat, but did not develop diabetes. If the scientists could make a drug to block PPAR- alpha, perhaps they could prevent diabetes. This research explains why the majority of people who develop diabetics are also obese.



Are you pre-diabetic? What can you do?

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http://drmirkin.blogspot.com/2006/04/whats-connection-between-obesity-and.html


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Mannatech Plus

Another product my midwife shared with me about: Mannatech Plus. I found this site that discussed it. Endometriosis Mannatech PlusAn excellent natural product with no side effects. I would highly recommend this product to anyone. I suffered extreme endometriosis for many years. I had two surgeries and used many different drugs and therapies. Plus was [...]

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http://harshrealities.info/nutrition/?p=246


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European Aspartame Manufacturer Quits

Holland Sweetener Company, a joint venture between Dutch Royal DSM and Japanese Tosoh Corporation has announced that it will close its Aspartame manufacturing facility located in the Netherlands. According to the financial pages of the Frankfurter Allgemeine Zeitung, the move is due to a "structural oversupply" in the global aspartame markets, which has caused "worldwide strong price erosion over the last 5 years". Perhaps recent renewed doubts over cancer causing properties and other side effects of the sweetener, which is used instead of sugar in a huge number of 'diet' foods and drinks, had something to do with the oversupply - Betty Martini, long time anti-aspartame campaigner, certainly thinks so....

Read The Full Article:
http://www.newmediaexplorer.org/sepp/2006/04/01/european_aspartame_manufacturer_q
uits.htm


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